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大学総合

教員・研究者教員・研究紹介

福森 良(ふくもり りょう)助教

福森 良

所属

薬学部 薬学科

専門分野

薬理学、分子薬理学

研究テーマ

グルタミン酸神経毒性関連疾患の神経精神薬理学

担当科目

薬理学実習、基本科学実習

所属学会

日本薬理学会、日本神経精神薬理学会、日本薬学会、日本神経化学会

研究室

薬学棟L101号室(薬理学)

連絡先

TEL:0956-20-5611(薬学事務室) FAX:0956-20-5622

E-mail

fukumori

URL

プロフィール

2008年 金沢大学大学院 自然科学研究科博士前期課程 入学
2010年 金沢大学大学院 自然科学研究科博士前期課程 修了
2010年 金沢大学大学院 自然科学研究科博士後期課程 入学
2013年 金沢大学大学院 自然科学研究科博士後期課程 修了
2013年 長崎国際大学 薬学部 薬理学研究室 助教 現職

研究活動

受賞

2009年8月 International Society for Neurochemistry Travel Awards 受賞
2010年6月 JSNP Excellent Presentation Award for CINP 2010 受賞
2010年11月 日本薬学会北陸支部第122回例会大学院優秀発表賞 受賞

研究実績

原著論文

<英文原著>
1. Bin Gu*, Noritaka Nakamichi*, Wen-Sheng Zhang, Yukary Nakamura, Yuki Kambe, Ryo Fukumori, Kazuhiro Takuma, Kiyofumi Yamada, Takeshi Takarada, Hideo Taniura and Yukio Yoneda. Possible protection by notoginsenoside R1 against neurotoxicity of N-methyl-D-aspartate receptor composed of an NR1/NR2B heteromeric assembly. J. Neurosci. Res. 87, 2145-2156. 2009. *Equally contributed.
2. Ryo Fukumori*, Noritaka Nakamichi*, Takeshi Takarada, Yuki Kambe, Nobuyuki Matsushima, Nobuaki Moriguchi and Yukio Yoneda. Inhibition by 2-methoxy-4-ethylphenol of Ca2+ influx through acquired and native N-methyl-D-aspartate receptor channels. J. Pharmacol. Sci. 112, 273-281. 2010. *Equally contributed.
3. Yuki Kambe, Noritaka Nakamichi, Takeshi Takarada, Ryo Fukumori and Yukio Yoneda. Induced tolerance to glutamate neurotoxicity through downregulation of NR2 subunits of N-methyl-D-aspartate receptors in cultured rat striatal neurons. J. Neurosci. Res. 88, 2177-2187. 2010.
4. Noritaka Nakamichi*, Ryo Fukumori*, Takeshi Takarada, Yuki Kambe, Tomomi Yamamoto, Nobuyuki Matsushima, Nobuaki Moriguchi and Yukio Yoneda. Preferential inhibition by antidiarrheic 2-methoxy-4-methylphenol of Ca2+ influx across acquired N-methyl-D-aspartate receptor channels composed of NR1/NR2B subunit assembly. J. Neurosci. Res. 88, 2483-2493. 2010. *Equally contributed.
5. Ryo Fukumori, Takeshi Takarada, Noritaka Nakamichi, Yuki Kambe, Hirofumi Kawagoe, Ryota Nakazato and Yukio Yoneda. Requirement of both NR3A and NR3B subunits for dominant negative properties on Ca2+ mobilization mediated by acquired N-methyl-D-aspartate receptor channels into mitochondria. Neurochem. Int. 57, 730-737. 2010.
6. Yuki Kambe, Noritaka Nakamichi, Takeshi Takarada, Ryo Fukumori, Ryota Nakazato, Eiichi Hinoi and Yukio Yoneda. A pivotal role of mitochondrial free calcium in neurotoxicity mediated by N-methyl-D-aspartate receptors in cultured rat hippocampal neurons. Neurochem. Int. 59, 10-20. 2011.
7. Takahisa Gono*, Takeshi Takarada*, Ryo Fukumori, Yasushi Kawaguchi, Hirotaka Kaneko, Masanori Hanaoka, Yasuhiro Katsumata, Yukio Yoneda and Hisashi Yamanaka. NR2-reactive antibody decreases cell viability through augmentation of Ca2+ influx in systemic lupus erythematosus. Arthritis Rheum. 63, 3952-3959. 2011. *Equally contributed.
8. Koichi Fujikawa*, Noritaka Nakamichi*, Shunsuke Kato, Ryo Fukumori, Miho Hida, Takeshi Takarada and Yukio Yoneda. Delayed mitochondrial membrane potential disruption by ATP in cultured rat hippocampal neurons exposed to N-methyl-D-aspartate. J. Pharmacol. Sci. 119, 20-29. 2012. *Equally contributed.
9. Ryo Fukumori*, Takeshi Takarada*, Yuki Kambe, Ryota Nakazato, Koichi Fujikawa and Yukio Yoneda. Possible involvement of mitochondrial uncoupling protein-2 in cytotoxicity mediated by acquired N-methyl-D-aspartate receptor channels. Neurochem. Int. 61, 498-505. 2012. *Equally contributed.
10. Takeshi Takarada*, Noritaka Nakamichi*, Hirofumi Kawagoe, Masato Ogura, Ryo Fukumori, Ryota Nakazato, Koichi Fujikawa, Miki Kou and Yukio Yoneda. Possible neuroprotective property of nicotinic acetylcholine receptors in association with predominant upregulation of glial cell line-derived neurotrophic factor in astrocytes. J. Neurosci. Res. 90, 2074-2085. 2012. *Equally contributed.
11.Takeshi Takarada*, Noritaka Nakamichi*, Seiya Kitajima, Ryo Fukumori, Ryota Nakazato, Nguyen Quynh Le, Yeong-Hun Kim, Koichi Fujikawa, Miki Kou and Yukio Yoneda. Promoted neuronal differentiation after activation of alpha4/beta2 nicotinic acetylcholine receptors in undifferentiated neural progenitors. PLoS ONE, e46177. 2012. *Equally contributed.
12 .Masato Ogura*, Takami Kakuda*, Takeshi Takarada*, Noritaka Nakamichi, Ryo Fukumori, Yeong-Hun Kim, Eiichi Hinoi and Yukio Yoneda. Promotion of both proliferation and differentiation in pluripotent P19 cells with stable overexpression of the glutamine transporter Slc38a1. PLoS ONE, e48270. 2012. *Equally contributed.

学会発表

<国際学会発表(筆頭発表者のみ)>
1. Ryo Fukumori, Noritaka Nakamichi, Yuki Kambe, Hideo Taniura, Takeshi Takarada and Yukio Yoneda. (2009). Properties of acquired NMDA channels in HEK293 cells. The 22nd Biennial Meeting of the ISN/APSN Joint Meeting, 23-28 August, Busan, Korea.
2. Ryo Fukumori, Yuki Kambe, Takeshi Takarada, Yukio Yoneda (2009). NMDA Receptor Channels Artificially Expressed in HEK293 cells. The 1st Meeting of the Asian College of Neuropsychopharmacology (AsCNP)・第19回 日本臨床精神神経薬理学会・第39回 日本神経精神薬理学会 合同年会. 13-15 November, Kyoto
3. Ryo Fukumori, Noritaka Nakamichi, Yuki Kambe, Takeshi Takarada and Yukio Yoneda (2010). Acquired NMDA channels artificially expressed in HEK293 cells. CINP 2010 World Congress , 6-10 June, Hong Kong, China
4. Ryo Fukumori, Takeshi Takarada and Yukio Yoneda (2011). Properties of acquired NMDAR channels expressed in HEK293 cells. ISN-ESN-2011, 28 Aug -1 Sep, Athens, Greek
5. Ryo Fukumori, Takeshi Takarada and Yukio Yoneda (2012). A role of mitochondrial uncoupling protein-2 in NMDA neuroxicity. 11th Biennial Meeting of APSN and 55th Meeting of JSN, Sep 30 - Oct 2, Kobe

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