Academic Research Staff and Principal AchievementAchievement
Professor
SASAKI Shigeki
![SASAKI Shigeki](https://teacher.niu.ac.jp/content/images/face/face367.jpg)
Published Papers
Manipulating nucleic acids - regulation of gene expression through higher order structure and chemical modification
Drug Delivery System 2024-01-25
Site-Specific Tritium Labeling at the Predefined Internal Position of the Chemically-Modified RNA
Chemical and Pharmaceutical Bulletin 2023-01-01
Recognition of 5-methyl-CG and CG base pairs in duplex DNA with high stability using antiparallel-type triplex-forming oligonucleotides with 2-guanidinoethyl-2'-deoxynebularine.
Nucleic acids research 2022-12-01
Application of the Functionality Transfer Oligodeoxynucleotide for the Site-Selective Modification of RNA with a Divers Molecule
Chemical and Pharmaceutical Bulletin 2022-07-01
Multiple-turnover single nucleotide primer extension reactions to detect 8-oxo-2′-deoxyguanosine in DNA
Chemical Communications 2022-04
Development of a selective ligand for G–G mismatches of CGG repeat RNA inducing the RNA structural conversion from the G-quadruplex into a hairpin-like structure
Organic and Biomolecular Chemistry 2022-04
Simple and Easy Synthesis of γ-Amido-dNTPs in Water and Their Polymerase Reaction Properties
Chemical and Pharmaceutical Bulletin 2021-11-01
Artificial Host Molecules to Covalently Capture 8-Nitro-cGMP in Neutral Aqueous Solutions and in Cells
Bioconjugate Chemistry 2021-02-17
Development of MTH1-Binding Nucleotide Analogs Based on 7,8-Dihalogenated 7-Deaza-dG Derivatives
International Journal of Molecular Sciences 2021-01-28
Design and synthesis of purine nucleoside analogues for the formation of stable anti-parallel-type triplex DNA with duplex DNA bearing the 5mCG base pair
RSC Advances 2021
MISC
Adenosine-1,3-diazaphenoxazine Derivative for Selective Base Pair Formation with 8-Oxo-2 '-deoxyguanosine in DNA (vol 133, pg 7272, 2011)
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2011-07
Synthesis of Reactive Oligonucleotides for Gene Targeting and Their Application to Gene Expression Regulation
Bulletin of the Chemical Society of Japan 2010-07
A new usage of functionalized oligodeoxynucleotide probe for site-specific modification of a guanine base within RNA
NUCLEIC ACIDS RESEARCH 2010-03
Recognition of CG interrupting site by W-shaped nucleoside analogs (WNA) having the pyrazole ring in an anti-parallel triplex DNA
BIOORGANIC & MEDICINAL CHEMISTRY 2009-10
Site-Specific Covalent Modification of RNA Guided by Functionality-Transfer Oligodeoxynucleotides
BIOCONJUGATE CHEMISTRY 2009-04
Incorporation of an inducible nucleotide analog into DNA by DNA polymerases
BIOORGANIC & MEDICINAL CHEMISTRY 2009-04
Selective fluorescence quenching of the 8-oxoG-clamp by 8-oxodeoxyguanosine in ODN
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 2009-02
A NEW ODORLESS PROCEDURE FOR THE SYNTHESIS OF 2 '-DEOXY-6-THIOGUANOSINE AND ITS INCORPORATION INTO OLIGODEOXYNUCLEOTIDES
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS 2009